INSTITUTION OVERVIEW
Institution Overview

Treatment Plans
9
Physicians
10+
Cell Processing
In-House CPC
Prime District
Ginza 6-chome
Ginza YR's public materials list regenerative medicine directions including autologous adipose-derived mesenchymal stem cell therapy, NK/alpha-beta T cell-related immunotherapy, and PRP therapy, covering joints, skin, hair, immune-related care, and functional wellness contexts. Its in-house CPC supports coordinated cell collection, processing, and treatment workflows. TWI includes it as a key documented institution based on public filing information, physician background materials, facility information, and documentation reviewed during coordination.
DOCTOR SPOTLIGHT
Medical Team

Junya Higuchi | Clinic Director
Ph.D. in Medicine, University of Tokyo | JSRM Certified Regenerative Medicine Physician
Ph.D. in Medicine
University of Tokyo
Japanese Society for Regenerative Medicine
Certified Regenerative Medicine Physician
Japanese Orthopaedic Association
Board-Certified Orthopedic Specialist
Japan Sports Association
Certified Sports Physician
Areas of Expertise
Regenerative Medicine | Orthopedics
Outpatient Experience
20,000+
Surgical Cases
1,000+
For a regenerative medicine institution, physicians are not merely decorative information; they are a key basis for judging professionalism and clinical scope. Ginza YR is worth closer attention precisely because it is supported by a University of Tokyo Ph.D. in Medicine, a JSRM-certified regenerative medicine physician, and an expert team.
Research & Clinical Practice
1) Associations of clinical outcomes and MRI findings in intra-articular administration of autologous adipose-derived stem cells for knee osteoarthritis. Regen Ther. 2020.
2) Relationship between medial partite hallux sesamoid and hallux valgus in the general population. Foot Ankle Surg. 2023.
3) Association of Preoperative Depression Score With Outcomes of Transfibular Total Ankle Arthroplasty. J Foot Ankle Surg. 2023.
4) The discrepancy between radiographically-assessed and self-recognized hallux valgus in a large population-based cohort. BMC Musculoskelet Disord. 2022.
5) Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development. Nat Commun. 2022.
6) Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human. Stem Cell Res Ther. 2021.
TREATMENT REFERENCES
Treatment References
Organized into three categories to help you quickly understand the scope of available programs. Each item includes a brief clinical description.
Regenerative Medicine

Autologous Stem Cell Therapy
Public filings list both intravenous and local-injection directions. Cell counts, processing details, administration route, and suitability should be confirmed through physician assessment and clinic documentation.
PRP Therapy
Derived from the patient's own blood, with public filing information covering chronic arthritis, skin regeneration, and hair regeneration directions. Preparation method, injection site, frequency, and contraindications should be confirmed during consultation.
Immune Cell Therapy
Public filing information includes NK cell and alpha-beta T cell immunotherapy directions related to cancer. These entries do not imply guaranteed outcomes; suitability must be assessed by the physician.
Regenerative Wellness

iPS Cell Exosome Infusion
Described around iPS cell-sourced exosomes and often discussed in wellness-maintenance consultations. Ingredient source, preparation standards, evidence boundaries, and suitability should be confirmed through clinic documentation and physician assessment.
Umbilical Cord Stem Cell Composite Exosome
Often discussed in wellness maintenance and anti-aging consultation contexts. Source, processing method, quality statement, administration route, risk disclosure, and personal suitability should be confirmed before deciding.
NAD⁺ β-NMN Infusion
NAD⁺ is a core coenzyme in cellular energy metabolism, and age-related decline is discussed in relation to fatigue and cognitive changes. IV use, expected role, and suitability should be evaluated with the clinic and physician.
Other Wellness Infusions
Includes high-dose vitamin C infusion, glutathione brightening infusion, and fatigue recovery infusion, with formulations tailored to individual conditions.
Aesthetic Medicine

Skin Rejuvenation
The clinic's skin program centers on the U225 meso-injection device, using high-precision microneedle technology to deliver active ingredients evenly into the dermis for improved elasticity, fine lines, and overall skin texture. Compatible with iPS exosomes, umbilical cord composite exosomes, and PRP.
Injectable Treatments
Includes Sunekos amino acid-hyaluronic acid composite injections and Botox neurotoxin injections. Sunekos primarily targets dermal collagen regeneration; Botox addresses dynamic wrinkles and contour management. Each has distinct indications and assessment criteria, with treatment plans determined by the physician.
IPL / Photon Therapy & Skin Quality Management
Uses the Cutera Xeo multi-platform system, with adjustable parameters for pigmentation, pore refinement, and skin tone uniformity. Suitable as a maintenance complement to injectable or regenerative programs, with specific protocols determined through physician evaluation.
IN-HOUSE CPC
Cell Processing Center (CPC)
In-house cell culture and preparation facility operating under JSRM-certified physician oversight. Key features include: serum-free culture medium, DMSO-free processing, and non-frozen cell delivery protocols.

Clean Zoning & Environmental Monitoring
Built on standardized environmental controls and monitoring to ensure key procedures remain controllable and traceable.
Standardized Culture Process
Structured around process management and quality control to support stable and consistent cell handling.
In-House Collection–Culture–Treatment Loop
Enables smoother coordination across key steps and reduces uncertainty associated with inter-institutional transfer.
COMPLIANCE
Qualifications & Registrations
For a regenerative medicine institution, treatment names alone are not sufficient for evaluation. What matters more is whether it provides publicly verifiable filing information and clear procedural boundaries. Ginza YR is notably transparent in this respect.


Specified Cell Processing
Notification of Manufacturing for Specified Cell-Processed Products
FC3250098
Class II | Local Injection
Autologous Adipose-Derived Stem Cell Therapy for Joint Disorders
PB3250224
Class II | IV Therapy for Pain Management
Autologous Adipose-Derived Stem Cell IV Therapy for Pain Management
PB3250226
Class II | Skin Regeneration
Autologous Adipose-Derived Stem Cell Therapy for Skin Regeneration
PB3250279
Class II | Hair Regeneration
Autologous Adipose-Derived Stem Cell Therapy for Hair Regeneration
PB3250305
Class II | PRP Joint Therapy
PRP Therapy for Chronic Arthritis
PB3250225
Class III | PRP Hair
PRP Therapy for Hair Regeneration
PC3250242
Class III | PRP Skin
PRP Therapy for Skin Regeneration
PC3250241
Class III | NK Cells
NK Cell Immunotherapy for Cancer
PC3250228
Class III | αβT Cells
Alpha-Beta T Cell Immunotherapy for Cancer
PC3250227
All of the above registrations can be publicly verified through the official database of Japan's Ministry of Health, Labour and Welfare (Regenerative Medicine Provider Database).
IN-CLINIC ENVIRONMENT
In-Clinic Environment
The clinic includes dedicated spaces for CPC cell processing, consultation, treatment, liposuction, a powder room, and pharmacy. Operating on a fully appointment-based model, the clinic prioritizes cleanliness, privacy, and overall patient experience. The intentionally understated interior reflects the director's philosophy: professional care over elaborate decor.


FREQUENTLY ASKED QUESTIONS
