Treatments · Wellness infusions

NAD+ IV Therapy in Japan: What It Does, the Process, and Precautions

What it is
A coenzyme in cellular energy metabolism
Delivery
Intravenous infusion (NMN and other precursors also used)
Regulation in Japan
Self-pay infusion; not a Regenerative Medicine Act registration
Time
Same day; infusion usually an hour or more
Visits
Can fit around other plans
Reference cost
Written quote after consultation
On this page
  1. 01What an NAD+ infusion is
  2. 02Common reasons people ask
  3. 03The process
  4. 04Who it suits, and who needs assessment first
  5. 05Reference cost
  6. 06Questions to ask at your consultation
  7. 07Frequently asked questions

Short answer

NAD+ is a coenzyme involved in cellular energy metabolism, and research shows levels fall with age. An NAD+ infusion delivers it directly into a vein and is commonly chosen for energy, fatigue, and healthy-aging maintenance. In Japan it is self-pay care done in one day, but it must be infused slowly, usually for an hour or more.

01

What an NAD+ infusion is

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme cells need to produce energy, and it is also involved in processes such as DNA repair. Research shows NAD+ levels decline with age.

An NAD+ infusion delivers NAD+ directly into a vein. Some clinics use NMN, a precursor of NAD+, such as the NAD+ β-NMN infusion at Ginza YR Clinic. Unlike oral supplements, an infusion bypasses digestion.

Worth knowing: clinical research on NAD+ infusions in humans is still building and results vary. It is best considered a maintenance option rather than treatment for a disease.

02

Common reasons people ask

These are common situations, not promises of results.

Energy and fatigue

Demanding work or long-term tiredness, looking at maintenance options.

Healthy aging

Part of a routine, often combined with other infusions.

Alongside other treatments

Scheduled before or after stem cell or exosome treatment.

03

The process

  1. Consultation

    Medical questions, with blood tests if needed.

  2. Infusion

    Given slowly, usually an hour or more. Too fast can cause chest tightness, nausea, or flushing; the rate can be reduced.

  3. Observation

    Normal activity the same day.

  4. Next steps

    The physician advises how often to repeat.

04

Who it suits, and who needs assessment first

Generally suited

  • Interested in maintenance options with limited time
  • Understand that results vary
  • Comfortable with a longer infusion

Physician assessment needed first

  • Pregnancy or breastfeeding
  • Serious liver or kidney problems
  • Cancer currently under treatment
  • Taking several medications (tell the physician)

05

Reference cost

NAD+ infusion costs vary by dose and number of sessions. We confirm a written quote with the clinic before you travel.

Whether tax is included and whether pricing is per session or a package is confirmed in the clinic's written quote. Coordination fees are explained separately.

How costs are made up and confirmed

06

Questions to ask at your consultation

  1. 01NAD+ or NMN, and how many milligrams?
  2. 02How long does the infusion take?
  3. 03How often, and how many sessions in total?
  4. 04Is the price per session or a package?
  5. 05What happens if I feel unwell?

07

Frequently asked questions

What is the difference between NAD+ and NMN?

NMN is a building block (precursor) the body uses to make NAD+. An NAD+ infusion supplies NAD+ directly; an NMN infusion supplies the precursor for the body to convert. The physician advises which suits you.

Infusion or oral supplements?

An infusion goes straight into the blood without digestion; oral supplements are easier and cheaper. Research comparing long-term effects in humans is limited.

Are there side effects?

If infused too quickly, chest tightness, nausea, flushing, or headache can occur, usually easing when the rate is slowed. Tell the physician about any conditions or medications.

How often should I have it?

There is no single standard; the physician advises based on your goal and health.

Written by Zhuoyue in Tokyo·Updated 2026-10-08

We provide visit coordination for Ginza YR Clinic.

This page is for general information and is not medical advice, diagnosis, or a guarantee of results. Suitability, treatment plans, and costs are confirmed by the treating physician and the clinic in writing.

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